JOINT CARE SUPPLEMENTS
What Is Glucosomine?
Glucosamine is an amino sugar compound produced by
the body. It is common in the liver and kidneys, but
most often found in cartilage. Glucosamine is effective
in building new cartilage and aids the repair of damaged
cartilage thereby cushioning joints, relieving pain,
and reducing inflammation.
Glucosamine is extracted from the tissues of shellfish
such as green lipped mussels, crab and lobster. Alternatively,
it may be synthetically produced as glucosamine sulfates,
which are often combined with chondroitin sulfates.
These sulfates may not be as potent as extracted glucosamine.
The treatment effect is equivalent to that achieved
through taking non-steroidal anti-inflammatory medications,
or NSAIDS, such as aspirin and ibuprofen, but with fewer
side effects than NSAIDS.
How Glucosomine Works
Healthy cartilage needs three things:
- Water for lubrication and nourishment
- Proteoglycans to attract and hold the water
- Collagen to keep the proteoglycans in place
Proteoglycans threads itself through the collagen
effectively hydrating, lubricating and nourishing the
collagen. When cartilage is damaged, these threads weaken
and the liquids escape.
As the collagen loses its nourishment, the proteoglycans
lose their grip and float away. The effect is that the
cartilage can no longer withstand shocks or cracks and
may wear out completely.
Glucosamine works by:
- acting as a stimulus to the cells that produce
proteoglycans and is a key determinant in how many
proteoglycans are produced by the cells
- speeds up production of collagen
- normalises cartilage metabolism
By helping to keep cartilage from breaking down, glucosamine
can help the body repair damaged or eroded cartilage.
So whilst glucosomine does not repair the cartilage
directly, it strengthens the body's natural repair mechanisms.
This reduces joint pain and inflammation.
500 - 800 mg twice a day, morning and evening with
food. Pills are preferable to the liquid; liquid glucosomine
is better absorbed.
Best taken in combination with condroitin. Both glucosamine
and chondroitin sulfate [measured as total disaccharides]
are bioavailable after oral dosing
Glucosomine Side Effects
Taking glucosomine on an empty stomach can cause problems
for some people.
NOTE: Those allergic to shellfish should take care
when using this product, although shellfish allergies
relate to proteins found in shellfish.
Glucosamine is not recommended for children.
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